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Current Research

Current Research

Research # 1

Hospital-Based Violence Intervention Program and Trauma Recovery Center

In partnership with the Departments of Trauma and Psychiatry, we have ongoing projects administering programming around the Hospital-Based Violence Intervention Program (HBVIP) and the Trauma Recovery Center (TRC) as well as conducting ongoing research projects involving HBVIP and the TRC.

Research # 2

Medication Assisted Therapy/Substance Use Disorder

We have a dedicated substance use disorder navigator to help individuals with substance use disorder. We also partner with the Whole Person Care Substance Use Disorder program to ensure that our patients receive the right care. We are working in partnership with the Bridge program to assess opiate use disorder. We are also researching medication-assisted therapy for alcohol use disorder.

Research # 3

Social EM Curriculum for Residents

Dedicated didactic and interactive small group teaching sessions are set aside during conference and teaching rounds to strengthen residents’ foundations in understanding the social factors affecting our patients’ health. Some of the topics have included violence, housing, incarceration, food insecurity, immigration, language, and gender identity.

Research # 4

Social EM Curriculum for Subinternships

This study aims to determine the effect of a required educational intervention on the attitudes and understanding of third- and fourth-year medical students enrolled in the Emergency Medicine subinternship. In a randomized manner, students receive the educational intervention either at the middle or end of their rotation. The goal is to evaluate the ability of medical students to address social barriers to care faced by patients in the emergency department and how this changes after the required educational intervention.

Research # 5

The Impact of SB 1152

Senate Bill 1152 (SB1152) was passed on January 1st, 2019. Proposed in California, this bill aims to improve the discharge process for homeless patients and decrease “patient dumping” by hospitals. Under this legislation, hospitals must provide patients who are homeless with food, weather-appropriate clothing, medications, referrals to social services, and transportation at the time of discharge. This project intends to quantify the impact of SB1152 on the hospital system as well as on patients experiencing homelessness.

We will analyze the impact of SB1152 on the medical system using emergency department (ED) length of stay. We will use 30-day ED revisit data to quantify the impact of SB1152 on homeless patients. The major concern with homeless discharge planning is that patients are discharged when they are too sick or insufficiently resourced to care for themselves and they end up back in the hospital.

Research # 6

Chatbot Screening for Social Needs

This project started as a collaboration between Harbor-UCLA’s Department of Emergency Medicine and the Department of Human Centered Design and Engineering to develop, study, and deploy an automated way of screening for social determinants in the emergency department. The chatbot (think Alexa or Siri) is web-based and can run on phones, tablets, or computers and asks patients about social needs. In the future, it will connect patients to resources via the 1 Degree platform (www.1deg.org). The project has now expanded to a multi-center study including Harbor-UCLA, Harborview Medical Center (Seattle, WA), and New York-Presbyterian Hospital.

Research # 7

Pediatric Social Needs Screening

Multiple studies have demonstrated the utility of emergency department-based social needs screening and navigation, yet best practice guidelines are lacking. This project, through a randomized controlled trial, directly investigates family preferences around screening during their child’s visit to the pediatric emergency department. Results may help inform patients and families of navigation programs not just within Harbor-UCLA but in other emergency departments as well.

Recently Completed Research

Early Convalescent Plasma for High-Risk Outpatients With COVID-19

The administration of Covid-19 convalescent plasma to high-risk outpatients within 1 week after the onset of symptoms of Covid-19 did not prevent disease progression.

Comparison of Outcomes of Antibiotic Drugs and Appendectomy (CODA) Trial

For the treatment of appendicitis, antibiotics were non-inferior to appendectomy based on the results of a standard health status measure. In the antibiotics group, nearly 3 in 10 participants had undergone appendectomy by 90 days. Participants with an appendicolith were at a higher risk for appendectomy and complications than those without an appendicolith.

A Randomized Controlled Trial on the Effect of a Double Check on the Detection of Medication Errors

The use of a double-check by two nurses has been advocated as a key error-prevention strategy. This study aims to determine how often a double-check is used for high-alert medications and whether it increases error detection.

A Multifaceted Intervention Improves Prescribing for Acute Respiratory Infection for Adults and Children in Emergency Department and Urgent Care Settings

It is common to prescribe antibiotics during emergency department and urgent care center visits for viral acute respiratory infections. We evaluate the comparative effectiveness of an antibiotic stewardship intervention adapted for acute care ambulatory settings (adapted intervention) to a stewardship intervention that additionally incorporates behavioral nudges (enhanced intervention) in reducing inappropriate prescriptions.

Multicenter Comparison of Nonsupine vs. Supine Positioning During Intubation in the Emergency Department: A National Emergency Airway Registry (NEAR) Study

Head-up positioning for preoxygenation and ramping for morbidly obese patients are well-accepted techniques, but the effect of head-up positioning with full torso elevation for all intubations is controversial. We compared first-pass success, adverse events, and glottic view between supine (SP) and nonsupine (NSP) positioning for emergency department (ED) patients undergoing orotracheal intubation.

Screening for Adolescent Alcohol Use in the Emergency Department: What Does It Tell Us About Cannabis, Tobacco, and Other Drug Use?

The pediatric emergency department (PED) represents an opportune time for alcohol and drug screening. The National Institute of Alcohol Abuse and Alcoholism (NIAAA) recommends a two-question alcohol screen for adolescents as a predictor of alcohol and drug misuse. A multi-site PED study was conducted to determine the association between the NIAAA two-question alcohol screen and adolescent cannabis use disorders (CUD), cigarette smoking, and lifetime use of other drugs.

Buccally Absorbed vs. Intravenous Prochlorperazine for Treatment of Migraine Headaches

This involved carrying out a randomized double-blind clinical trial to compare the efficacy of buccally absorbed prochlorperazine (BAP) to intravenous prochlorperazine (IVP) for the abortive treatment of migraine headaches.

Teaching Endotracheal Intubation Using a Cadaver vs. a Manikin-based Model: A Randomized Controlled Trial

The optimal method to train novice learners to perform endotracheal intubation (ETI) is unknown. The study objective was to compare two models: unembalmed cadaver vs. simulation manikin.

Subdissociative-Dose Ketamine Is Effective for Treating Acute Exacerbations of Chronic Pain

Subdissociative-dose ketamine (SDDK) is used to treat acute pain. This study was a randomized double-blind placebo-controlled trial that sought to determine if SDDK is effective in relieving acute exacerbations of chronic pain.

Selected Recent Publications from 2018 to Present

Social EM

Clinical Care

Research Methodology

Education

Pediatrics

EMS

Other